Can current molecular tests help in the diagnosis of indeterminate thyroid nodule FNAB?

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The Mcgill thyroid nodule score – does it help with indeterminate thyroid nodules?

BACKGROUND Ultrasound guided fine-needle aspiration (USFNA) biopsy of thyroid nodules often gives a result of indeterminate pathology, placing thyroid specialists in difficult management situations. The aim of this study is to evaluate the incidence of malignancy in patients undergoing surgery and to correlate these results with the McGill Thyroid Nodule Score (MTNS). METHODS We performed a r...

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Molecular Signature of Indeterminate Thyroid Lesions: Current Methods to Improve Fine Needle Aspiration Cytology (FNAC) Diagnosis

Fine needle aspiration cytology (FNAC) represents the gold standard for determining the nature of thyroid nodules. It is a reliable method with good sensitivity and specificity. However, indeterminate lesions remain a diagnostic challenge and researchers have contributed molecular markers to search for in cytological material to refine FNAC diagnosis and avoid unnecessary surgeries. Nowadays, s...

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A Pragmatic Approach to the Indeterminate Thyroid Nodule

Thyroid nodules are prevalent in upto 68% of randomly selected individuals in whom high resolution ultrasound is performed. The majority of nodules are benign. The use of ultrasound coupled with FNAC has dramatically reduced the number of patients who undergo surgery for nodules. The six tier Bethesda scoring system has reduced variability and increased the ability to clinicians to guide patien...

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Can a hot nodule disappear in thyroid scintigraphy without any therapies?

A 63-year-old woman presented with a history of hyperthyroidism symptoms over two years, referred for thyroid scintigraphy. In the hospital archives we have met her previous thyroid scintigraphy showing a hot nodule in the upper part of right thyroid lobe. However, her recent thyroid scintigraphy was showing only cold nodules but no hot nodule, giving an impression that she had some treatment t...

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ژورنال

عنوان ژورنال: Archives of Endocrinology and Metabolism

سال: 2018

ISSN: 2359-3997,2359-4292

DOI: 10.20945/2359-3997000000081